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Quantitative detection of low-abundance somatic structural variants in normal cells by high throughput sequencing
The detection and quantification of low-abundance somatic DNA mutations by high throughput sequencing is challenging because of the difficulty in distinguishing errors from true mutations. While there are several approaches available for analyzing somatic point mutations and small indels, an accurat...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927357/ https://www.ncbi.nlm.nih.gov/pubmed/27271197 http://dx.doi.org/10.1038/nmeth.3893 |