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Efficacy of Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis: an open-label dose-ranging study

BACKGROUND: Cryptococcus is the most common cause of adult meningitis in Africa. We evaluated the activity of adjunctive sertraline, previously demonstrated to have in vitro and in vivo activity against Cryptococcus. METHODS: We enrolled 172 HIV-infected Ugandans with cryptococcal meningitis from Au...

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Detalles Bibliográficos
Autores principales:	Rhein, Joshua, Morawski, Bozena M, Hullsiek, Kathy Huppler, Nabeta, Henry W, Kiggundu, Reuben, Tugume, Lillian, Musubire, Abdu, Akampurira, Andrew, Smith, Kyle D, Alhadab, Ali, Williams, Darlisha A, Abassi, Mahsa, Bahr, Nathan C, Velamakanni, Sruti S, Fisher, James, Nielsen, Kirsten, Meya, David B, Boulware, David R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927382/ https://www.ncbi.nlm.nih.gov/pubmed/26971081 http://dx.doi.org/10.1016/S1473-3099(16)00074-8

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