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Huntington’s Disease Protein Huntingtin Associates with its own mRNA

Background: The Huntington’s disease (HD) protein huntingtin (Htt) plays a role in multiple cellular pathways. Deregulation of one or more of these pathways by the mutant Htt protein has been suggested to contribute to the disease pathogenesis. Our recent discovery-based proteomics studies have unco...

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Detalles Bibliográficos
Autores principales:	Culver, Brady P., DeClercq, Josh, Dolgalev, Igor, Yu, Man Shan, Ma, Bin, Heguy, Adriana, Tanese, Naoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2016
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927879/ https://www.ncbi.nlm.nih.gov/pubmed/26891106 http://dx.doi.org/10.3233/JHD-150177

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