Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein

Besides the hallmark pathology of amyloid plaques and neurofibrillary tangles, it is well documented that cyclin-dependent kinase 5 (CDK5), a critical neuronal protein kinase in nervous system development, function, and survival, when deregulated and hyperactivated induces Alzheimer’s disease (AD) a...

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Detalles Bibliográficos
Autores principales: Binukumar, B.K., Shukla, Varsha, Amin, Niranjana D., Bhaskar, Manju, Skuntz, Suzanne, Steiner, Joseph, Winkler, Dirk, Pelech, Steven L., Pant, Harish C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927891/
https://www.ncbi.nlm.nih.gov/pubmed/26444778
http://dx.doi.org/10.3233/JAD-150412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927891/
https://www.ncbi.nlm.nih.gov/pubmed/26444778
http://dx.doi.org/10.3233/JAD-150412

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