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Cycloheximide Treatment Causes a ZVAD-Sensitive Protease-Dependent Cleavage of Human Tau in Drosophila Cells

Neurofibrillary tangles are the main pathological feature of Alzheimer’s disease. Insoluble tau protein is the major component of neurofibrillary tangles. Defects in the tau protein degradation pathway in neurons can lead to the accumulation of tau and its subsequent aggregation. Currently, contradi...

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Detalles Bibliográficos
Autores principales:	Geng, Junhua, Xia, Lu, Li, Wanjie, Zhao, Changqi, Dou, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927919/ https://www.ncbi.nlm.nih.gov/pubmed/26599052 http://dx.doi.org/10.3233/JAD-150423

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