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Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination

Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide, accounting for about 9.6 million new cases and 1.5 million deaths annually. The poorest and socially excluded groups carry the largest burden of disease, which makes it essential to properly address the social determinants of...

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Detalles Bibliográficos
Autores principales: Raviglione, Mario, Sulis, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927938/
https://www.ncbi.nlm.nih.gov/pubmed/27403269
http://dx.doi.org/10.4081/idr.2016.6570
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author Raviglione, Mario
Sulis, Giorgia
author_facet Raviglione, Mario
Sulis, Giorgia
author_sort Raviglione, Mario
collection PubMed
description Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide, accounting for about 9.6 million new cases and 1.5 million deaths annually. The poorest and socially excluded groups carry the largest burden of disease, which makes it essential to properly address the social determinants of health through poverty reduction measures and targeted interventions on high-risk populations. The spread of multidrug-resistance TB requires special attention and highlights the need to foster research on TB diagnostics, new drugs and vaccines. Although many advances have been made in the fight against TB over the last twenty years, a lot is still needed to achieve global elimination. The new end-TB strategy that was first launched in 2014 by the World Health Organization, is fully in line with the seventeen Sustainable Development Goals that came into effect since January 2016 and sets ambitious goals for the post-2015 agenda. A 90% reduction in TB-related mortality and an 80% decline in TB incidence within 2030 as well as the abolition of catastrophic expenditures for TB-affected people are the main targets of this strategy. Strong government commitment and adequate financing from all countries together with community engagement and appropriate investments in research are necessary in order to reach these objectives.
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spelling pubmed-49279382016-07-11 Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination Raviglione, Mario Sulis, Giorgia Infect Dis Rep Review Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide, accounting for about 9.6 million new cases and 1.5 million deaths annually. The poorest and socially excluded groups carry the largest burden of disease, which makes it essential to properly address the social determinants of health through poverty reduction measures and targeted interventions on high-risk populations. The spread of multidrug-resistance TB requires special attention and highlights the need to foster research on TB diagnostics, new drugs and vaccines. Although many advances have been made in the fight against TB over the last twenty years, a lot is still needed to achieve global elimination. The new end-TB strategy that was first launched in 2014 by the World Health Organization, is fully in line with the seventeen Sustainable Development Goals that came into effect since January 2016 and sets ambitious goals for the post-2015 agenda. A 90% reduction in TB-related mortality and an 80% decline in TB incidence within 2030 as well as the abolition of catastrophic expenditures for TB-affected people are the main targets of this strategy. Strong government commitment and adequate financing from all countries together with community engagement and appropriate investments in research are necessary in order to reach these objectives. PAGEPress Publications, Pavia, Italy 2016-06-24 /pmc/articles/PMC4927938/ /pubmed/27403269 http://dx.doi.org/10.4081/idr.2016.6570 Text en ©Copyright M. Raviglione and G.Sulis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Raviglione, Mario
Sulis, Giorgia
Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination
title Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination
title_full Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination
title_fullStr Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination
title_full_unstemmed Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination
title_short Tuberculosis 2015: Burden, Challenges and Strategy for Control and Elimination
title_sort tuberculosis 2015: burden, challenges and strategy for control and elimination
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927938/
https://www.ncbi.nlm.nih.gov/pubmed/27403269
http://dx.doi.org/10.4081/idr.2016.6570
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