Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility

Changes in vascular permeability occur during inflammation and the actin cytoskeleton plays a crucial role in regulating endothelial cell contacts and permeability. We demonstrated recently that the actin-binding protein cortactin regulates vascular permeability via Rap1. However, it is unknown if t...

Descripción completa

Detalles Bibliográficos
Autores principales: García Ponce, Alexander, Citalán Madrid, Alí F., Vargas Robles, Hilda, Chánez Paredes, Sandra, Nava, Porfirio, Betanzos, Abigail, Zarbock, Alexander, Rottner, Klemens, Vestweber, Dietmar, Schnoor, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928053/
https://www.ncbi.nlm.nih.gov/pubmed/27357373
http://dx.doi.org/10.1038/srep29003

Ejemplares similares

Ejemplares similares