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KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily

BACKGROUND: The association between aberrant signal processing by protein kinases and human diseases such as cancer was established long time ago. However, understanding the link between sequence variants in the protein kinase superfamily and the mechanistic complex traits at the molecular level rem...

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Detalles Bibliográficos
Autores principales:	Pons, Tirso, Vazquez, Miguel, Matey-Hernandez, María Luisa, Brunak, Søren, Valencia, Alfonso, Izarzugaza, Jose MG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928150/ https://www.ncbi.nlm.nih.gov/pubmed/27357839 http://dx.doi.org/10.1186/s12864-016-2723-1

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