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A loss of function variant in CASP7 protects against Alzheimer’s disease in homozygous APOE ε4 allele carriers

BACKGROUND: Alzheimer’s disease (AD) represents the most common form of dementia in elder populations with approximately 30 million cases worldwide. Genome wide genotyping and sequencing studies have identified many genetic variants associated with late-onset Alzheimer’s disease (LOAD). While most o...

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Detalles Bibliográficos
Autores principales:	Ayers, Kristin L., Mirshahi, Uyenlinh L., Wardeh, Amr H., Murray, Michael F., Hao, Ke, Glicksberg, Benjamin S., Li, Shuyu, Carey, David J., Chen, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928152/ https://www.ncbi.nlm.nih.gov/pubmed/27358062 http://dx.doi.org/10.1186/s12864-016-2725-z

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