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A Structure-free Method for Quantifying Conformational Flexibility in proteins

All proteins sample a range of conformations at physiologic temperatures and this inherent flexibility enables them to carry out their prescribed functions. A comprehensive understanding of protein function therefore entails a characterization of protein flexibility. Here we describe a novel approac...

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Detalles Bibliográficos
Autores principales: Burger, Virginia M., Arenas, Daniel J., Stultz, Collin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928179/
https://www.ncbi.nlm.nih.gov/pubmed/27358108
http://dx.doi.org/10.1038/srep29040