Loss of Lipid Virulence Factors Reduces the Efficacy of the BCG Vaccine

Bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is the only vaccine available for tuberculosis (TB) control. BCG comprises a number of substrains that exhibit genetic and biochemical differences. Whether and how these differences affect BCG efficacy remain unknown. Compar...

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Detalles Bibliográficos
Autores principales: Tran, Vanessa, Ahn, Sang Kyun, Ng, Mark, Li, Ming, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928182/
https://www.ncbi.nlm.nih.gov/pubmed/27357109
http://dx.doi.org/10.1038/srep29076

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