Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity

Interferons (IFNs) are key cytokines identified in vertebrates and evolutionary dominance of intronless IFN genes in amniotes is a signature event in IFN evolution. For the first time, we show that the emergence and expansion of intronless IFN genes is evident in amphibians, shown by 24–37 intronles...

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Detalles Bibliográficos
Autores principales: Sang, Yongming, Liu, Qinfang, Lee, Jinhwa, Ma, Wenjun, McVey, D. Scott, Blecha, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928184/
https://www.ncbi.nlm.nih.gov/pubmed/27356970
http://dx.doi.org/10.1038/srep29072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928184/
https://www.ncbi.nlm.nih.gov/pubmed/27356970
http://dx.doi.org/10.1038/srep29072

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