A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging

A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presenc...

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Detalles Bibliográficos
Autores principales: Liu, Zonglun, Gao, Kuo, Wang, Beng, Yan, Hui, Xing, Panfei, Zhong, Chongmin, Xu, Yongqian, Li, Hongjuan, Chen, Jianxin, Wang, Wei, Sun, Shiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928191/
https://www.ncbi.nlm.nih.gov/pubmed/27356618
http://dx.doi.org/10.1038/srep29065
Descripción
Sumario:A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presence of HClO and successfully imaged HClO in living cell and living mouse.

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