A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging

A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presenc...

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Autores principales: Liu, Zonglun, Gao, Kuo, Wang, Beng, Yan, Hui, Xing, Panfei, Zhong, Chongmin, Xu, Yongqian, Li, Hongjuan, Chen, Jianxin, Wang, Wei, Sun, Shiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928191/
https://www.ncbi.nlm.nih.gov/pubmed/27356618
http://dx.doi.org/10.1038/srep29065
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author Liu, Zonglun
Gao, Kuo
Wang, Beng
Yan, Hui
Xing, Panfei
Zhong, Chongmin
Xu, Yongqian
Li, Hongjuan
Chen, Jianxin
Wang, Wei
Sun, Shiguo
author_facet Liu, Zonglun
Gao, Kuo
Wang, Beng
Yan, Hui
Xing, Panfei
Zhong, Chongmin
Xu, Yongqian
Li, Hongjuan
Chen, Jianxin
Wang, Wei
Sun, Shiguo
author_sort Liu, Zonglun
collection PubMed
description A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presence of HClO and successfully imaged HClO in living cell and living mouse.
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spelling pubmed-49281912016-07-06 A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging Liu, Zonglun Gao, Kuo Wang, Beng Yan, Hui Xing, Panfei Zhong, Chongmin Xu, Yongqian Li, Hongjuan Chen, Jianxin Wang, Wei Sun, Shiguo Sci Rep Article A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presence of HClO and successfully imaged HClO in living cell and living mouse. Nature Publishing Group 2016-06-30 /pmc/articles/PMC4928191/ /pubmed/27356618 http://dx.doi.org/10.1038/srep29065 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Liu, Zonglun
Gao, Kuo
Wang, Beng
Yan, Hui
Xing, Panfei
Zhong, Chongmin
Xu, Yongqian
Li, Hongjuan
Chen, Jianxin
Wang, Wei
Sun, Shiguo
A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging
title A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging
title_full A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging
title_fullStr A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging
title_full_unstemmed A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging
title_short A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging
title_sort dinuclear ruthenium(ii) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928191/
https://www.ncbi.nlm.nih.gov/pubmed/27356618
http://dx.doi.org/10.1038/srep29065
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