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AirLab: a cloud-based platform to manage and share antibody-based single-cell research

Single-cell analysis technologies are essential tools in research and clinical diagnostics. These methods include flow cytometry, mass cytometry, and other microfluidics-based technologies. Most laboratories that employ these methods maintain large repositories of antibodies. These ever-growing coll...

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Autores principales: Catena, Raúl, Özcan, Alaz, Jacobs, Andrea, Chevrier, Stephane, Bodenmiller, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928244/
https://www.ncbi.nlm.nih.gov/pubmed/27356760
http://dx.doi.org/10.1186/s13059-016-1006-0
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author Catena, Raúl
Özcan, Alaz
Jacobs, Andrea
Chevrier, Stephane
Bodenmiller, Bernd
author_facet Catena, Raúl
Özcan, Alaz
Jacobs, Andrea
Chevrier, Stephane
Bodenmiller, Bernd
author_sort Catena, Raúl
collection PubMed
description Single-cell analysis technologies are essential tools in research and clinical diagnostics. These methods include flow cytometry, mass cytometry, and other microfluidics-based technologies. Most laboratories that employ these methods maintain large repositories of antibodies. These ever-growing collections of antibodies, their multiple conjugates, and the large amounts of data generated in assays using specific antibodies and conditions makes a dedicated software solution necessary. We have developed AirLab, a cloud-based tool with web and mobile interfaces, for the organization of these data. AirLab streamlines the processes of antibody purchase, organization, and storage, antibody panel creation, results logging, and antibody validation data sharing and distribution. Furthermore, AirLab enables inventory of other laboratory stocks, such as primers or clinical samples, through user-controlled customization. Thus, AirLab is a mobile-powered and flexible tool that harnesses the capabilities of mobile tools and cloud-based technology to facilitate inventory and sharing of antibody and sample collections and associated validation data. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-016-1006-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-49282442016-06-30 AirLab: a cloud-based platform to manage and share antibody-based single-cell research Catena, Raúl Özcan, Alaz Jacobs, Andrea Chevrier, Stephane Bodenmiller, Bernd Genome Biol Open Letter Single-cell analysis technologies are essential tools in research and clinical diagnostics. These methods include flow cytometry, mass cytometry, and other microfluidics-based technologies. Most laboratories that employ these methods maintain large repositories of antibodies. These ever-growing collections of antibodies, their multiple conjugates, and the large amounts of data generated in assays using specific antibodies and conditions makes a dedicated software solution necessary. We have developed AirLab, a cloud-based tool with web and mobile interfaces, for the organization of these data. AirLab streamlines the processes of antibody purchase, organization, and storage, antibody panel creation, results logging, and antibody validation data sharing and distribution. Furthermore, AirLab enables inventory of other laboratory stocks, such as primers or clinical samples, through user-controlled customization. Thus, AirLab is a mobile-powered and flexible tool that harnesses the capabilities of mobile tools and cloud-based technology to facilitate inventory and sharing of antibody and sample collections and associated validation data. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-016-1006-0) contains supplementary material, which is available to authorized users. BioMed Central 2016-06-29 /pmc/articles/PMC4928244/ /pubmed/27356760 http://dx.doi.org/10.1186/s13059-016-1006-0 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Open Letter
Catena, Raúl
Özcan, Alaz
Jacobs, Andrea
Chevrier, Stephane
Bodenmiller, Bernd
AirLab: a cloud-based platform to manage and share antibody-based single-cell research
title AirLab: a cloud-based platform to manage and share antibody-based single-cell research
title_full AirLab: a cloud-based platform to manage and share antibody-based single-cell research
title_fullStr AirLab: a cloud-based platform to manage and share antibody-based single-cell research
title_full_unstemmed AirLab: a cloud-based platform to manage and share antibody-based single-cell research
title_short AirLab: a cloud-based platform to manage and share antibody-based single-cell research
title_sort airlab: a cloud-based platform to manage and share antibody-based single-cell research
topic Open Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928244/
https://www.ncbi.nlm.nih.gov/pubmed/27356760
http://dx.doi.org/10.1186/s13059-016-1006-0
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