Cargando…

Assessment of clinically related outcomes and biomarker analysis for translational integration in colorectal cancer (ACROBATICC): study protocol for a population-based, consecutive cohort of surgically treated colorectal cancers and resected colorectal liver metastasis

BACKGROUND: More accurate predictive and prognostic biomarkers for patients with colorectal cancer (CRC) primaries or colorectal liver metastasis (CLM) are needed. Outside clinical trials, the translational integration of emerging pathways and novel techniques should facilitate exploration of biomar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Søreide, Kjetil, Watson, Martin M., Lea, Dordi, Nordgård, Oddmund, Søreide, Jon Arne, Hagland, Hanne R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928276/ https://www.ncbi.nlm.nih.gov/pubmed/27357108 http://dx.doi.org/10.1186/s12967-016-0951-4

Ejemplares similares

Elevated microsatellite alterations at selected tetranucleotides in early‐stage colorectal cancers with and without high‐frequency microsatellite instability: same, same but different?
por: Watson, Martin M., et al.
Publicado: (2016)

Prevalence of PD-L1 expression is associated with EMAST, density of peritumoral T-cells and recurrence-free survival in operable non-metastatic colorectal cancer
por: Watson, Martin M., et al.
Publicado: (2020)

Elevated Microsatellite Alterations at Selected Tetranucleotides (EMAST) Is Not Attributed to MSH3 Loss in Stage I-III Colon cancer: An Automated, Digitalized Assessment by Immunohistochemistry of Whole Slides and Hot Spots()()
por: Watson, Martin M, et al.
Publicado: (2019)

Time to halt perioperative chemotherapy for resectable colorectal liver metastasis?
por: Søreide, Kjetil
Publicado: (2021)

Histopathological Growth Pattern in Colorectal Liver Metastasis and The Tumor Immune Microenvironment
por: Zaharia, Claudia, et al.
Publicado: (2022)

KRAS mutation in patients undergoing hepatic resection for colorectal liver metastasis: A biomarker of cancer biology or a byproduct of patient selection?
por: Søreide, Kjetil, et al.
Publicado: (2014)

A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment
por: Lea, Dordi, et al.
Publicado: (2021)

Can molecular biomarkers replace a clinical risk score for resectable colorectal liver metastasis?
por: Veen, Torhild, et al.
Publicado: (2017)

Genetic and Epigenetic Traits as Biomarkers in Colorectal Cancer
por: Berg, Marianne, et al.
Publicado: (2011)

Resection of asymptomatic primary tumour in unresectable stage IV colorectal cancer: time to move on from propensity matched scores to randomized controlled trials
por: Søreide, Kjetil
Publicado: (2016)

Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines
por: Tidwell, Tia R., et al.
Publicado: (2022)

Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells
por: Alhourani, Abdelnour H., et al.
Publicado: (2021)

Author Correction: Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells
por: Alhourani, Abdelnour H., et al.
Publicado: (2022)

Comparison of CpG Island Methylator Phenotype (CIMP) Frequency in Colon Cancer Using Different Probe- and Gene-Specific Scoring Alternatives on Recommended Multi-Gene Panels
por: Berg, Marianne, et al.
Publicado: (2014)

Aging, Metabolism, and Cancer Development: from Peto’s Paradox to the Warburg Effect
por: Tidwell, Tia R., et al.
Publicado: (2017)

Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer
por: Veen, Torhild, et al.
Publicado: (2023)

Molecular Subtypes in Stage II-III Colon Cancer Defined by Genomic Instability: Early Recurrence-Risk Associated with a High Copy-Number Variation and Loss of RUNX3 and CDKN2A
por: Berg, Marianne, et al.
Publicado: (2015)

Digital Image Analysis of the Proliferation Markers Ki67 and Phosphohistone H3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Accuracy of Grading Compared With Routine Manual Hot Spot Evaluation of the Ki67 Index
por: Lea, Dordi, et al.
Publicado: (2021)

The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer
por: Oltedal, Satu, et al.
Publicado: (2018)

Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps
por: Kleive, Dyre, et al.
Publicado: (2021)

Neoadjuvant immunotherapy in primary and metastatic colorectal cancer
por: Kanani, A, et al.
Publicado: (2021)

Long-Term Follow-Up and Survivorship After Completing Systematic Surveillance in Stage I–III Colorectal Cancer: Who Is Still at Risk?
por: Veen, T., et al.
Publicado: (2015)

Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
por: Lind, Guro E., et al.
Publicado: (2017)

Scoring systems for outcome prediction in patients with perforated peptic ulcer
por: Thorsen, Kenneth, et al.
Publicado: (2013)

What Is the Best Predictor of Mortality in Perforated Peptic Ulcer Disease? A Population-Based, Multivariable Regression Analysis Including Three Clinical Scoring Systems
por: Thorsen, Kenneth, et al.
Publicado: (2014)

The overriding role of surgery and tumor grade for long‐term survival in patients with gastroenteropancreatic neuroendocrine neoplasms: A population‐based cohort study
por: Søreide, Jon Arne, et al.
Publicado: (2021)

Emerging Concepts of Apolipoprotein D with Possible Implications for Breast Cancer
por: Søiland, Håvard, et al.
Publicado: (2007)

Using Patient-Reported Outcome Measures for Improved Decision-Making in Patients with Gastrointestinal Cancer – the Last Clinical Frontier in Surgical Oncology?
por: Søreide, Kjetil, et al.
Publicado: (2013)

Genetic Characteristics of Resectable Colorectal Cancer with Pulmonary Metastasis
por: Qiu, Yan-Yu, et al.
Publicado: (2022)

Neoadjuvant and Adjuvant Therapy in Operable Pancreatic Cancer: Both Honey and Milk (but No Bread?)
por: Søreide, Kjetil
Publicado: (2021)

Complications as indicators of quality assurance after 401 consecutive colorectal cancer resections: the importance of surgeon volume in developing colorectal cancer units in India
por: Shetty, Guruprasad S, et al.
Publicado: (2012)

Trends in Diagnosis and Surgical Management of Patients with Perforated Peptic Ulcer
por: Thorsen, Kenneth, et al.
Publicado: (2011)

Primary Leiomyosarcoma of the Pancreas—a Case Report and a Comprehensive Review
por: Søreide, Jon Arne, et al.
Publicado: (2016)

Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
por: Berg, Kaja C. G., et al.
Publicado: (2019)

Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis
por: Søreide, Kjetil, et al.
Publicado: (2020)

The prognostic relevance of examined lymph nodes for accurate staging of resected pancreatic adenocarcinoma
por: Zaharia, Claudia, et al.
Publicado: (2022)

Acute mesenteric ischaemia
por: Fuglseth, Hanne, et al.
Publicado: (2023)

Call for better response evaluation after neoadjuvant therapy in pancreatic cancer
por: Zaharia, Claudia, et al.
Publicado: (2023)

Hepatic resection margin predicts survival in colorectal cancer with hepatic metastasis
por: Choi, Jin Hyuk, et al.
Publicado: (2012)

Aggressive surgical resection for concomitant liver and lung metastasis in colorectal cancer
por: Lee, Sung Hwan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_d8pjkn19io8mov99qp6oo53qkj