Reference-free deconvolution of DNA methylation data and mediation by cell composition effects

BACKGROUND: Recent interest in reference-free deconvolution of DNA methylation data has led to several supervised methods, but these methods do not easily permit the interpretation of underlying cell types. RESULTS: We propose a simple method for reference-free deconvolution that provides both propo...

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Detalles Bibliográficos
Autores principales: Houseman, E. Andres, Kile, Molly L., Christiani, David C., Ince, Tan A., Kelsey, Karl T., Marsit, Carmen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928286/
https://www.ncbi.nlm.nih.gov/pubmed/27358049
http://dx.doi.org/10.1186/s12859-016-1140-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928286/
https://www.ncbi.nlm.nih.gov/pubmed/27358049
http://dx.doi.org/10.1186/s12859-016-1140-4

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