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Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome
OBJECTIVE: To determine the biochemical and hormonal differences in polycystic ovary syndrome (PCOS) patients with and without polycystic ovary (PCO) morphology and to evaluate the outcomes resulting from those differences. METHODS: The study included a total of 83 patients with PCOS; 43 of them had...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Professional Medical Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928434/ https://www.ncbi.nlm.nih.gov/pubmed/27375725 http://dx.doi.org/10.12669/pjms.323.10082 |
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author | Inan, Cihan Karadag, Cihan |
author_facet | Inan, Cihan Karadag, Cihan |
author_sort | Inan, Cihan |
collection | PubMed |
description | OBJECTIVE: To determine the biochemical and hormonal differences in polycystic ovary syndrome (PCOS) patients with and without polycystic ovary (PCO) morphology and to evaluate the outcomes resulting from those differences. METHODS: The study included a total of 83 patients with PCOS; 43 of them had PCO morphology (Group-I) and 40 did not (Group-II). Serum LDL, HDL, total cholesterol, triglyceride (TG), total testosterone (T), follicle stimulating hormone (FSH), luteinizing hormone (LH), 17b-estradiol (E2), prolactin (PRL), thyroid stimulating hormone (TSH), sex hormone binding globulin (SHBG), glucose and insulin levels were determined. Homoeostatic model assessment insulin resistance (HOMA-IR) index was calculated. RESULTS: The two groups were similar with respect to BMI. The systolic and diastolic blood pressure measurements of Group-I were significantly lower (p<0.01). Serum mean level of LH (p=0.026) and the mean LH/FSH (p=0.001) level of Group-I were significantly higher than Group-II. The total cholesterol and triglyceride levels of Group-I were significantly lower (p<0.05, p<0.01). The mean HOMA-IR level of Group-I was significantly lower than Group-II (p=0.004). CONCLUSIONS: The group without PCO morphology had a higher risk than the other group in terms of increased insulin resistance, dyslipidemia and cardiovascular diseases due to effects of hyperandrogenism. |
format | Online Article Text |
id | pubmed-4928434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Professional Medical Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-49284342016-07-01 Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome Inan, Cihan Karadag, Cihan Pak J Med Sci Original Article OBJECTIVE: To determine the biochemical and hormonal differences in polycystic ovary syndrome (PCOS) patients with and without polycystic ovary (PCO) morphology and to evaluate the outcomes resulting from those differences. METHODS: The study included a total of 83 patients with PCOS; 43 of them had PCO morphology (Group-I) and 40 did not (Group-II). Serum LDL, HDL, total cholesterol, triglyceride (TG), total testosterone (T), follicle stimulating hormone (FSH), luteinizing hormone (LH), 17b-estradiol (E2), prolactin (PRL), thyroid stimulating hormone (TSH), sex hormone binding globulin (SHBG), glucose and insulin levels were determined. Homoeostatic model assessment insulin resistance (HOMA-IR) index was calculated. RESULTS: The two groups were similar with respect to BMI. The systolic and diastolic blood pressure measurements of Group-I were significantly lower (p<0.01). Serum mean level of LH (p=0.026) and the mean LH/FSH (p=0.001) level of Group-I were significantly higher than Group-II. The total cholesterol and triglyceride levels of Group-I were significantly lower (p<0.05, p<0.01). The mean HOMA-IR level of Group-I was significantly lower than Group-II (p=0.004). CONCLUSIONS: The group without PCO morphology had a higher risk than the other group in terms of increased insulin resistance, dyslipidemia and cardiovascular diseases due to effects of hyperandrogenism. Professional Medical Publications 2016 /pmc/articles/PMC4928434/ /pubmed/27375725 http://dx.doi.org/10.12669/pjms.323.10082 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Inan, Cihan Karadag, Cihan Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome |
title | Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome |
title_full | Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome |
title_fullStr | Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome |
title_full_unstemmed | Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome |
title_short | Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome |
title_sort | correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928434/ https://www.ncbi.nlm.nih.gov/pubmed/27375725 http://dx.doi.org/10.12669/pjms.323.10082 |
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