Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia

Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) success...

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Detalles Bibliográficos
Autores principales: Sorà, Federica, Chiusolo, Patrizia, Laurenti, Luca, Autore, Francesco, Giammarco, Sabrina, Sica, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928521/
https://www.ncbi.nlm.nih.gov/pubmed/27413520
http://dx.doi.org/10.4084/MJHID.2016.027
Descripción
Sumario:Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) successfully treated with thrombolysis for PE and heparin. APL has been processed with a combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) obtaining complete remission.

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