Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia

Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) success...

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Detalles Bibliográficos
Autores principales: Sorà, Federica, Chiusolo, Patrizia, Laurenti, Luca, Autore, Francesco, Giammarco, Sabrina, Sica, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928521/
https://www.ncbi.nlm.nih.gov/pubmed/27413520
http://dx.doi.org/10.4084/MJHID.2016.027
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author Sorà, Federica
Chiusolo, Patrizia
Laurenti, Luca
Autore, Francesco
Giammarco, Sabrina
Sica, Simona
author_facet Sorà, Federica
Chiusolo, Patrizia
Laurenti, Luca
Autore, Francesco
Giammarco, Sabrina
Sica, Simona
author_sort Sorà, Federica
collection PubMed
description Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) successfully treated with thrombolysis for PE and heparin. APL has been processed with a combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) obtaining complete remission.
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spelling pubmed-49285212016-07-13 Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia Sorà, Federica Chiusolo, Patrizia Laurenti, Luca Autore, Francesco Giammarco, Sabrina Sica, Simona Mediterr J Hematol Infect Dis Case Report Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) successfully treated with thrombolysis for PE and heparin. APL has been processed with a combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) obtaining complete remission. Università Cattolica del Sacro Cuore 2016-07-01 /pmc/articles/PMC4928521/ /pubmed/27413520 http://dx.doi.org/10.4084/MJHID.2016.027 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sorà, Federica
Chiusolo, Patrizia
Laurenti, Luca
Autore, Francesco
Giammarco, Sabrina
Sica, Simona
Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia
title Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia
title_full Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia
title_fullStr Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia
title_full_unstemmed Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia
title_short Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia
title_sort massive pulmonary embolism at the onset of acute promyelocytic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928521/
https://www.ncbi.nlm.nih.gov/pubmed/27413520
http://dx.doi.org/10.4084/MJHID.2016.027
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