Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia

Acute limb ischemia (ALI) is a common vascular emergency. Hematologic malignancies are commonly associated with derangement of normal hemostasis and thrombo-hemorrhagic symptoms during the course of the disease are common. However, ALI as an initial presenting feature of acute leukemia is rare. Due...

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Autores principales: Chotai, Pranit N., Kasangana, Kalenda, Chandra, Abhinav B., Rao, Atul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Vascular Specialist International 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928607/
https://www.ncbi.nlm.nih.gov/pubmed/27386455
http://dx.doi.org/10.5758/vsi.2016.32.2.65
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author Chotai, Pranit N.
Kasangana, Kalenda
Chandra, Abhinav B.
Rao, Atul S.
author_facet Chotai, Pranit N.
Kasangana, Kalenda
Chandra, Abhinav B.
Rao, Atul S.
author_sort Chotai, Pranit N.
collection PubMed
description Acute limb ischemia (ALI) is a common vascular emergency. Hematologic malignancies are commonly associated with derangement of normal hemostasis and thrombo-hemorrhagic symptoms during the course of the disease are common. However, ALI as an initial presenting feature of acute leukemia is rare. Due to the rarity of this presentation, there is a scarcity of prospective randomized data to optimally guide the management of these patients. Current knowledge is mainly based on isolated cases. We report our experience managing a patient who presented with ALI and was found to have occult leukemia. A review of all cases with ALI as a presenting feature of acute leukemia is also presented.
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spelling pubmed-49286072016-07-07 Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia Chotai, Pranit N. Kasangana, Kalenda Chandra, Abhinav B. Rao, Atul S. Vasc Specialist Int Case Report Acute limb ischemia (ALI) is a common vascular emergency. Hematologic malignancies are commonly associated with derangement of normal hemostasis and thrombo-hemorrhagic symptoms during the course of the disease are common. However, ALI as an initial presenting feature of acute leukemia is rare. Due to the rarity of this presentation, there is a scarcity of prospective randomized data to optimally guide the management of these patients. Current knowledge is mainly based on isolated cases. We report our experience managing a patient who presented with ALI and was found to have occult leukemia. A review of all cases with ALI as a presenting feature of acute leukemia is also presented. Vascular Specialist International 2016-06 2016-06-30 /pmc/articles/PMC4928607/ /pubmed/27386455 http://dx.doi.org/10.5758/vsi.2016.32.2.65 Text en Copyright © 2016, The Korean Society for Vascular Surgery This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chotai, Pranit N.
Kasangana, Kalenda
Chandra, Abhinav B.
Rao, Atul S.
Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia
title Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia
title_full Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia
title_fullStr Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia
title_full_unstemmed Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia
title_short Recurrent Arterial Thrombosis as a Presenting Feature of a Variant M3-Acute Promyelocytic Leukemia
title_sort recurrent arterial thrombosis as a presenting feature of a variant m3-acute promyelocytic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928607/
https://www.ncbi.nlm.nih.gov/pubmed/27386455
http://dx.doi.org/10.5758/vsi.2016.32.2.65
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AT chandraabhinavb recurrentarterialthrombosisasapresentingfeatureofavariantm3acutepromyelocyticleukemia
AT raoatuls recurrentarterialthrombosisasapresentingfeatureofavariantm3acutepromyelocyticleukemia

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