The Phosphoinosotide 3-Kinase Catalytic Subunit p110α is Required for Normal Lens Growth

PURPOSE: Signal transduction pathways influence lens growth, but little is known about the role(s) of the class 1A phosphoinositide 3-kinases (PI3Ks). To further investigate how signaling regulates lens growth, we generated and characterized mice in which the p110α and p110β catalytic subunits of PI...

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Detalles Bibliográficos
Autores principales: Sellitto, Caterina, Li, Leping, Vaghefi, Ehsan, Donaldson, Paul J., Lin, Richard Z., White, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928694/
https://www.ncbi.nlm.nih.gov/pubmed/27304846
http://dx.doi.org/10.1167/iovs.16-19607

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