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DNA Hypermethylation of CREB3L1 and Bcl-2 Associated with the Mitochondrial-Mediated Apoptosis via PI3K/Akt Pathway in Human BEAS-2B Cells Exposure to Silica Nanoparticles

The toxic effects of silica nanoparticles (SiNPs) are raising concerns due to its widely applications in biomedicine. However, current information about the epigenetic toxicity of SiNPs is insufficient. In this study, the epigenetic regulation of low-dose exposure to SiNPs was evaluated in human bro...

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Detalles Bibliográficos
Autores principales:	Zou, Yang, Li, Qiuling, Jiang, Lizhen, Guo, Caixia, Li, Yanbo, Yu, Yang, Li, Yang, Duan, Junchao, Sun, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928798/ https://www.ncbi.nlm.nih.gov/pubmed/27362941 http://dx.doi.org/10.1371/journal.pone.0158475

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