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The Prerequisites for Central Tolerance Induction against Citrullinated Proteins in the Mouse

OBJECTIVES: To assess the prerequisites for negative selection of peptidylcitrulline-specific T cells in the thymus. In detail, we here analyzed murine medullary thymic epithelial cells for the expression of peptidylarginine deiminases (PAD) and subsequent citrullination. METHODS: Medullary thymic e...

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Detalles Bibliográficos
Autores principales:	Engelmann, Robby, Biemelt, Andra, Cordshagen, Antje, Johl, Anja, Kuthning, Daniela, Müller-Hilke, Brigitte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928850/ https://www.ncbi.nlm.nih.gov/pubmed/27362943 http://dx.doi.org/10.1371/journal.pone.0158773

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