CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

Herpesviruses infect the majority of the human population and can cause significant morbidity and mortality. Herpes simplex virus (HSV) type 1 causes cold sores and herpes simplex keratitis, whereas HSV-2 is responsible for genital herpes. Human cytomegalovirus (HCMV) is the most common viral cause...

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Detalles Bibliográficos
Autores principales: van Diemen, Ferdy R., Kruse, Elisabeth M., Hooykaas, Marjolein J. G., Bruggeling, Carlijn E., Schürch, Anita C., van Ham, Petra M., Imhof, Saskia M., Nijhuis, Monique, Wiertz, Emmanuel J. H. J., Lebbink, Robert Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928872/
https://www.ncbi.nlm.nih.gov/pubmed/27362483
http://dx.doi.org/10.1371/journal.ppat.1005701

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