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HIV and HCV Co-Culture Promotes Profibrogenic Gene Expression through an Epimorphin-Mediated ERK Signaling Pathway in Hepatic Stellate Cells

Accelerated fibrosis in patients co-infected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) has been a major cause of mortality in the highly active anti-retroviral therapy (HAART) era. However, the role of co-infection in accelerating the progression of liver fibrosis, particul...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Qin, Enqiang, Zhou, Junnian, Zhao, Juanjuan, Nie, Weimin, Jiang, Tianjun, Chen, Weiwei, Wu, Dan, Huang, Lei, Liu, Liying, Lv, Liping, Zhao, Min, Zhang, Zheng, Wang, Fusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928874/
https://www.ncbi.nlm.nih.gov/pubmed/27362846
http://dx.doi.org/10.1371/journal.pone.0158386