Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

Bacterial biofilms present a significant medical challenge because they are recalcitrant to current therapeutic regimes. A key component of biofilm formation in the opportunistic human pathogen Pseudomonas aeruginosa is the biosynthesis of the exopolysaccharides Pel and Psl, which are involved in th...

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Detalles Bibliográficos
Autores principales: Baker, Perrin, Hill, Preston J., Snarr, Brendan D., Alnabelseya, Noor, Pestrak, Matthew J., Lee, Mark J., Jennings, Laura K., Tam, John, Melnyk, Roman A., Parsek, Matthew R., Sheppard, Donald C., Wozniak, Daniel J., Howell, P. Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928890/
https://www.ncbi.nlm.nih.gov/pubmed/27386527
http://dx.doi.org/10.1126/sciadv.1501632

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