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Spontaneous mutations and the origin and maintenance of quantitative genetic variation

Mutation and natural selection shape the genetic variation in natural populations. Here, we directly estimated the spontaneous mutation rate by sequencing new Drosophila mutation accumulation lines maintained with minimal natural selection. We inferred strong stabilizing natural selection on quantit...

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Detalles Bibliográficos
Autores principales:	Huang, Wen, Lyman, Richard F, Lyman, Rachel A, Carbone, Mary Anna, Harbison, Susan T, Magwire, Michael M, Mackay, Trudy FC
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Genomics and Evolutionary Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929002/ https://www.ncbi.nlm.nih.gov/pubmed/27213517 http://dx.doi.org/10.7554/eLife.14625

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