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Rif1 Regulates the Fate of DNA Entanglements during Mitosis

Clearance of entangled DNA from the anaphase mid-region must accurately proceed in order for chromosomes to segregate with high fidelity. Loss of Taz1 (fission yeast ortholog of human TRF1/TRF2) leads to stalled telomeric replication forks that trigger telomeric entanglements; the resolution of thes...

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Detalles Bibliográficos
Autores principales: Zaaijer, Sophie, Shaikh, Nadeem, Nageshan, Rishi Kumar, Cooper, Julia Promisel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929174/
https://www.ncbi.nlm.nih.gov/pubmed/27320927
http://dx.doi.org/10.1016/j.celrep.2016.05.077