Suppressive action of miRNAs to ARP2/3 complex reduces cell migration and proliferation via RAC isoforms in Hirschsprung disease

Hirschsprung disease (HSCR) is a congenital disorder caused by the defective function of the embryonic enteric neural crest. The impaired migration of embryonic enteric neural crest plays an important role in the pathogenesis of this disease. Recent studies showed that the ARP2/3 complex and RAC iso...

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Detalles Bibliográficos
Autores principales: Tang, Weibing, Cai, Peng, Huo, Weiwei, Li, Hongxing, Tang, Junwei, Zhu, Dongmei, Xie, Hua, Chen, Pingfa, Hang, Bo, Wang, Shouyu, Xia, Yankai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929290/
https://www.ncbi.nlm.nih.gov/pubmed/26991540
http://dx.doi.org/10.1111/jcmm.12799

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