Cargando…

3D spheroid culture enhances survival and therapeutic capacities of MSCs injected into ischemic kidney

Three‐dimensional (3D) cell culture has been reported to increase the therapeutic potentials of mesenchymal stem cells (MSCs). In this study, we aimed to investigate the therapeutic effects of 3D spheroids of human adipose‐derived MSCs for acute kidney injury (AKI). In vitro studies indicated that 3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yong, Shi, Taoping, Xu, Axiang, Zhang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929304/ https://www.ncbi.nlm.nih.gov/pubmed/26914637 http://dx.doi.org/10.1111/jcmm.12651

Ejemplares similares

3D Spheroid Culture Enhances the Expression of Antifibrotic Factors in Human Adipose-Derived MSCs and Improves Their Therapeutic Effects on Hepatic Fibrosis
por: Zhang, Xuan, et al.
Publicado: (2016)

Hypoxia-Pretreated Human MSCs Attenuate Acute Kidney Injury through Enhanced Angiogenic and Antioxidative Capacities
por: Zhang, Wenbo, et al.
Publicado: (2014)

Three-dimensional culture of MSCs produces exosomes with improved yield and enhanced therapeutic efficacy for cisplatin-induced acute kidney injury
por: Cao, Jingyuan, et al.
Publicado: (2020)

The Multi-Therapeutic Role of MSCs in Diabetic Nephropathy
por: Wang, Yi, et al.
Publicado: (2021)

Shift of EMT gradient in 3D spheroid MSCs for activation of mesenchymal niche function
por: Jeon, Sohee, et al.
Publicado: (2017)

Embryonic Stem Cell‐Derived Mesenchymal Stem Cells (MSCs) Have a Superior Neuroprotective Capacity Over Fetal MSCs in the Hypoxic‐Ischemic Mouse Brain
por: Hawkins, Kate E., et al.
Publicado: (2018)

Immunomodulation and Regenerative Capacity of MSCs for Long-COVID
por: Loke, Xin Ya, et al.
Publicado: (2021)

Neovascularization: The Main Mechanism of MSCs in Ischemic Heart Disease Therapy
por: Shi, Weili, et al.
Publicado: (2021)

TUDCA-treated chronic kidney disease-derived hMSCs improve therapeutic efficacy in ischemic disease via PrP(C)
por: Yoon, Yeo Min, et al.
Publicado: (2019)

Substance P enhances the therapeutic effect of MSCs by modulating their angiogenic potential
por: Hong, Hyun Sook, et al.
Publicado: (2020)

Characteristics of MSCs in Synovial Fluid and Mode of Action of Intra-Articular Injections of Synovial MSCs in Knee Osteoarthritis
por: Sekiya, Ichiro, et al.
Publicado: (2021)

iPSC-Derived MSCs Are a Distinct Entity of MSCs with Higher Therapeutic Potential than Their Donor-Matched Parental MSCs
por: Lee, Hae-Ri, et al.
Publicado: (2023)

BM-MSCs overexpressing the Numb enhance the therapeutic effect on cholestatic liver fibrosis by inhibiting the ductular reaction
por: Xu, Yan-nan, et al.
Publicado: (2023)

Influence of Conditioned Media on the Re-Differentiation Capacity of Human Chondrocytes in 3D Spheroid Cultures
por: Klinder, Annett, et al.
Publicado: (2020)

3D Culture of MSCs on a Gelatin Microsphere in a Dynamic Culture System Enhances Chondrogenesis
por: Sulaiman, Shamsul, et al.
Publicado: (2020)

SPION-MSCs enhance therapeutic efficacy in sepsis by regulating MSC-expressed TRAF1-dependent macrophage polarization
por: Xu, Yujun, et al.
Publicado: (2021)

AF-MSCs fate can be regulated by culture conditions
por: Zagoura, D S, et al.
Publicado: (2013)

Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction
por: Wang, Yiyang, et al.
Publicado: (2022)

Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns
por: Masterson, Claire H., et al.
Publicado: (2019)

BDNF-overexpressing MSCs delivered by hydrogel in acute ischemic stroke treatment
por: Wang, Congxiao, et al.
Publicado: (2022)

Spheroid Culture of Mesenchymal Stem Cells
por: Cesarz, Zoe, et al.
Publicado: (2016)

Human serum enhances the proliferative capacity and immunomodulatory property of MSCs derived from human placenta and umbilical cord
por: Thaweesapphithak, Sermporn, et al.
Publicado: (2019)

Cell spheroids culture array with modifiable chemical gradients
por: Yang, Panhui, et al.
Publicado: (2023)

Senescence induces fundamental changes in the secretome of mesenchymal stromal cells (MSCs): implications for the therapeutic use of MSCs and their derivates
por: Siraj, Yesuf, et al.
Publicado: (2023)

The role of MSCs and CAR-MSCs in cellular immunotherapy
por: Yan, Lun, et al.
Publicado: (2023)

MSCs-laden injectable self-healing hydrogel for systemic sclerosis treatment
por: Nie, Min, et al.
Publicado: (2022)

Human fetal liver MSCs are more effective than adult bone marrow MSCs for their immunosuppressive, immunomodulatory, and Foxp3(+) T reg induction capacity
por: Yu, Yi, et al.
Publicado: (2021)

Mesenchymal stem cells (MSCs) as skeletal therapeutics–an update
por: Saeed, Hamid, et al.
Publicado: (2016)

MSCs vs. iPSCs: Potential in therapeutic applications
por: Thanaskody, Kalaiselvaan, et al.
Publicado: (2022)

Immunomodulatory Effect of MSCs and MSCs-Derived Extracellular Vesicles in Systemic Lupus Erythematosus
por: Yang, Chunjuan, et al.
Publicado: (2021)

Irisin Promotes Cardiac Homing of Intravenously Delivered MSCs and Protects against Ischemic Heart Injury
por: Yan, Wenjun, et al.
Publicado: (2022)

In Vivo Tracking and Comparison of the Therapeutic Effects of MSCs and HSCs for Liver Injury
por: Li, Qiang, et al.
Publicado: (2013)

Intercellular adhesion molecule-1 enhances the therapeutic effects of MSCs in a dextran sulfate sodium-induced colitis models by promoting MSCs homing to murine colons and spleens
por: Li, Xin, et al.
Publicado: (2019)

hiPSC‐derived iMSCs: NextGen MSCs as an advanced therapeutically active cell resource for regenerative medicine
por: Sabapathy, Vikram, et al.
Publicado: (2016)

An Improved Scalable Hydrogel Dish for Spheroid Culture
por: Valdoz, Jonard Corpuz, et al.
Publicado: (2021)

Exosomes derived from human umbilical cord MSCs rejuvenate aged MSCs and enhance their functions for myocardial repair
por: Zhang, Ning, et al.
Publicado: (2020)

Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis
por: Wang, Xiaofang, et al.
Publicado: (2014)

Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis
por: Wang, Xiaofang, et al.
Publicado: (2021)

Injectable ROS-scavenging hydrogel with MSCs promoted the regeneration of damaged skeletal muscle
por: Shan, Huajian, et al.
Publicado: (2021)

Encapsulation of MSCs and GDNF in an Injectable Nanoreinforced Supramolecular Hydrogel for Brain Tissue Engineering
por: Torres-Ortega, Pablo Vicente, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cerri2kq3k128cdpn77tqv7j5d