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Myocardial protective effects of a c‐Jun N‐terminal kinase inhibitor in rats with brain death

To investigate whether the mitochondrial apoptotic pathway mediates myocardial cell injuries in rats under brain death (BD), and observe the effects and mechanisms of the c‐Jun N‐terminal kinase (JNK) inhibitor SP600125 on cell death in the heart. Forty healthy male Sprague‐Dawley (SD) rats were ran...

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Detalles Bibliográficos
Autores principales: Guo, Wenzhi, Cao, Shengli, Yan, Bing, Zhang, Gong, Li, Jie, Zhao, Yongfu, Zhang, Shuijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929305/
https://www.ncbi.nlm.nih.gov/pubmed/27072084
http://dx.doi.org/10.1111/jcmm.12676