Acoustic trauma slows AMPA receptor‐mediated EPSCs in the auditory brainstem, reducing GluA4 subunit expression as a mechanism to rescue binaural function

KEY POINTS: Lateral superior olive (LSO) principal neurons receive AMPA receptor (AMPAR) ‐ and NMDA receptor (NMDAR)‐mediated EPSCs and glycinergic IPSCs. Both EPSCs and IPSCs have slow kinetics in prehearing animals, which during developmental maturation accelerate to sub‐millisecond decay time‐con...

Descripción completa

Detalles Bibliográficos
Autores principales: Pilati, Nadia, Linley, Deborah M., Selvaskandan, Haresh, Uchitel, Osvaldo, Hennig, Matthias H., Kopp‐Scheinpflug, Cornelia, Forsythe, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Neuroscience ‐ Cellular/Molecular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929335/
https://www.ncbi.nlm.nih.gov/pubmed/27104476
http://dx.doi.org/10.1113/JP271929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929335/
https://www.ncbi.nlm.nih.gov/pubmed/27104476
http://dx.doi.org/10.1113/JP271929

Ejemplares similares