Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current Solutions

Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic activity by specifically inhibiting the bacterial protein synthesis. In certa...

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Detalles Bibliográficos
Autores principales: Dinos, George P., Athanassopoulos, Constantinos M., Missiri, Dionissia A., Giannopoulou, Panagiota C., Vlachogiannis, Ioannis A., Papadopoulos, Georgios E., Papaioannou, Dionissios, Kalpaxis, Dimitrios L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929435/
https://www.ncbi.nlm.nih.gov/pubmed/27271676
http://dx.doi.org/10.3390/antibiotics5020020

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