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Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway
This study investigated the function of a chloride channel blocker, DIDS. Both in vitro and in vivo studies found that DIDS significantly inhibits lipopolysaccharide (LPS)-induced release of proin flammatory cytokines. Here, we show that DIDS inhibits LPS-induced inflammation, as shown by downregula...
Autores principales: | Xiang, Nan-lin, Liu, Jun, Liao, Yun-jian, Huang, You-wei, Wu, Zheng, Bai, Zhi-quan, Lin, Xi, Zhang, Jian-hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929440/ https://www.ncbi.nlm.nih.gov/pubmed/27363391 http://dx.doi.org/10.1038/srep27583 |
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