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Novel role of cortactin in G protein-coupled receptor agonist-induced nuclear export and degradation of p21Cip1
Monocyte chemotactic protein 1 (MCP1) stimulates phosphorylation of cortactin on Y421 and Y446 residues in a time-dependent manner and phosphorylation at Y446 but not Y421 residue is required for MCP1-induced CDK-interacting protein 1 (p21Cip1) nuclear export and degradation in facilitating human ao...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929470/ https://www.ncbi.nlm.nih.gov/pubmed/27363897 http://dx.doi.org/10.1038/srep28687 |