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S-adenosylmethionine reduces airway inflammation and fibrosis in a murine model of chronic severe asthma via suppression of oxidative stress
Increased oxidative stress has an important role in asthmatic airway inflammation and remodeling. A potent methyl donor, S-adenosylmethionine (SAMe), is known to protect against tissue injury and fibrosis through modulation of oxidative stress. The aim of this study was to evaluate the effect of SAM...
Autores principales: | Yoon, Sun-Young, Hong, Gyong Hwa, Kwon, Hyouk-Soo, Park, Sunjoo, Park, So Young, Shin, Bomi, Kim, Tae-Bum, Moon, Hee-Bom, Cho, You Sook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929690/ https://www.ncbi.nlm.nih.gov/pubmed/27256110 http://dx.doi.org/10.1038/emm.2016.35 |
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