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Notch1 hallmarks fibrillary depositions in sporadic Alzheimer’s disease

BACKGROUND: Notch1 signaling is a cellular cascade with a fundamental role from brain development to adult brain function. Reduction in Notch1 affects synaptic plasticity, memory and olfaction. On the other hand, Notch1 overactivation after brain injury is detrimental for neuronal survival. Some fam...

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Detalles Bibliográficos
Autores principales:	Brai, Emanuele, Alina Raio, Noemi, Alberi, Lavinia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929714/ https://www.ncbi.nlm.nih.gov/pubmed/27364742 http://dx.doi.org/10.1186/s40478-016-0327-2

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