A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody

Uterine cervical small cell carcinoma is rare and aggressive with no standardized therapy. A patient bearing the advanced chemo‐refractory carcinoma, treated with a tumor vaccine combined with 1 mg/kg of pembrolizumab, showed a transient increase and subsequent sharp decrease of the liver‐metastasiz...

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Autores principales: Miyoshi, Tatsu, Kataoka, Tatsuji, Asahi, Atsuko, Maruyama, Takashi, Okada, Rika, Uemae, Yoji, Ohno, Tadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929807/
https://www.ncbi.nlm.nih.gov/pubmed/27386130
http://dx.doi.org/10.1002/ccr3.596
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author Miyoshi, Tatsu
Kataoka, Tatsuji
Asahi, Atsuko
Maruyama, Takashi
Okada, Rika
Uemae, Yoji
Ohno, Tadao
author_facet Miyoshi, Tatsu
Kataoka, Tatsuji
Asahi, Atsuko
Maruyama, Takashi
Okada, Rika
Uemae, Yoji
Ohno, Tadao
author_sort Miyoshi, Tatsu
collection PubMed
description Uterine cervical small cell carcinoma is rare and aggressive with no standardized therapy. A patient bearing the advanced chemo‐refractory carcinoma, treated with a tumor vaccine combined with 1 mg/kg of pembrolizumab, showed a transient increase and subsequent sharp decrease of the liver‐metastasized lesion to less than half its maximum diameter.
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spelling pubmed-49298072016-07-06 A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody Miyoshi, Tatsu Kataoka, Tatsuji Asahi, Atsuko Maruyama, Takashi Okada, Rika Uemae, Yoji Ohno, Tadao Clin Case Rep Case Reports Uterine cervical small cell carcinoma is rare and aggressive with no standardized therapy. A patient bearing the advanced chemo‐refractory carcinoma, treated with a tumor vaccine combined with 1 mg/kg of pembrolizumab, showed a transient increase and subsequent sharp decrease of the liver‐metastasized lesion to less than half its maximum diameter. John Wiley and Sons Inc. 2016-06-09 /pmc/articles/PMC4929807/ /pubmed/27386130 http://dx.doi.org/10.1002/ccr3.596 Text en © 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Miyoshi, Tatsu
Kataoka, Tatsuji
Asahi, Atsuko
Maruyama, Takashi
Okada, Rika
Uemae, Yoji
Ohno, Tadao
A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody
title A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody
title_full A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody
title_fullStr A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody
title_full_unstemmed A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody
title_short A transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐PD‐1 antibody
title_sort transient increase and subsequent sharp decrease of chemo‐refractory liver‐metastasized uterine cervical small cell carcinoma to autologous formalin‐fixed tumor vaccine plus anti‐pd‐1 antibody
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929807/
https://www.ncbi.nlm.nih.gov/pubmed/27386130
http://dx.doi.org/10.1002/ccr3.596
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