Reduced protein synthesis in schizophrenia patient-derived olfactory cells

Human olfactory neurosphere-derived (ONS) cells have the potential to provide novel insights into the cellular pathology of schizophrenia. We used discovery-based proteomics and targeted functional analyses to reveal reductions in 17 ribosomal proteins, with an 18% decrease in the total ribosomal si...

Descripción completa

Detalles Bibliográficos
Autores principales: English, J A, Fan, Y, Föcking, M, Lopez, L M, Hryniewiecka, M, Wynne, K, Dicker, P, Matigian, N, Cagney, G, Mackay-Sim, A, Cotter, D R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930119/
https://www.ncbi.nlm.nih.gov/pubmed/26485547
http://dx.doi.org/10.1038/tp.2015.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930119/
https://www.ncbi.nlm.nih.gov/pubmed/26485547
http://dx.doi.org/10.1038/tp.2015.119

Ejemplares similares