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Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia
Antagonists of the N-methyl-D-aspartate (NMDA)-type glutamate receptor induce psychosis in healthy individuals and exacerbate schizophrenia symptoms in patients. In this study we have produced an animal model of NMDA receptor hypofunction by chronically treating rats with low doses of the NMDA recep...
Autores principales: | Ingason, A, Giegling, I, Hartmann, A M, Genius, J, Konte, B, Friedl, M, Ripke, S, Sullivan, P F, St. Clair, D, Collier, D A, O'Donovan, M C, Mirnics, K, Rujescu, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930128/ https://www.ncbi.nlm.nih.gov/pubmed/26460480 http://dx.doi.org/10.1038/tp.2015.151 |
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