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It All Starts with a Sandwich: Identification of Sialidases with Trans-Glycosylation Activity
Sialidases (3.2.1.18) may exhibit trans-sialidase activity to catalyze sialylation of lactose if the active site topology is congruent with that of the Trypanosoma cruzi trans-sialidase (EC 2.4.1.-). The present work was undertaken to test the hypothesis that a particular aromatic sandwich structure...
Autores principales: | Nordvang, Rune T., Nyffenegger, Christian, Holck, Jesper, Jers, Carsten, Zeuner, Birgitte, Sundekilde, Ulrik K., Meyer, Anne S., Mikkelsen, Jørn D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930215/ https://www.ncbi.nlm.nih.gov/pubmed/27367145 http://dx.doi.org/10.1371/journal.pone.0158434 |
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