A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo

Sepsis remains a leading cause of death worldwide. Despite years of extensive research, effective drugs to treat sepsis in the clinic are lacking. In this study, we found a novel imidazopyridine derivative, X22, which has powerful anti-inflammatory activity. X22 dose-dependently inhibited lipopolysa...

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Detalles Bibliográficos
Autores principales: Ge, Xiangting, Feng, Zhiguo, Xu, Tingting, Wu, Beibei, Chen, Hongjin, Xu, Fengli, Fu, Lili, Shan, Xiaoou, Dai, Yuanrong, Zhang, Yali, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930233/
https://www.ncbi.nlm.nih.gov/pubmed/27390516
http://dx.doi.org/10.2147/DDDT.S101449

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