Cargando…

Marine Sponges as a Drug Treasure

Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge’s derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral,...

Descripción completa

Detalles Bibliográficos
Autores principales: Anjum, Komal, Abbas, Syed Qamar, Shah, Sayed Asmat Ali, Akhter, Najeeb, Batool, Sundas, Hassan, Syed Shams ul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930278/
https://www.ncbi.nlm.nih.gov/pubmed/27350338
http://dx.doi.org/10.4062/biomolther.2016.067
_version_ 1782440727959044096
author Anjum, Komal
Abbas, Syed Qamar
Shah, Sayed Asmat Ali
Akhter, Najeeb
Batool, Sundas
Hassan, Syed Shams ul
author_facet Anjum, Komal
Abbas, Syed Qamar
Shah, Sayed Asmat Ali
Akhter, Najeeb
Batool, Sundas
Hassan, Syed Shams ul
author_sort Anjum, Komal
collection PubMed
description Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge’s derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral, antifungal, antimalarial, antitumor, immunosuppressive, and cardiovascular activity. Although, the mode of action of many compounds by which they interfere with human pathogenesis have not been clear till now, in this review not only the capability of the medicinal substances have been examined in vitro and in vivo against serious pathogenic microbes but, the mode of actions of medicinal compounds were explained with diagrammatic illustrations. This knowledge is one of the basic components to be known especially for transforming medicinal molecules to medicines. Sponges produce a different kind of chemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. The fact that different diseases have the capability to fight at different sites inside the body can increase the chances to produce targeted medicines.
format Online
Article
Text
id pubmed-4930278
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher The Korean Society of Applied Pharmacology
record_format MEDLINE/PubMed
spelling pubmed-49302782016-07-15 Marine Sponges as a Drug Treasure Anjum, Komal Abbas, Syed Qamar Shah, Sayed Asmat Ali Akhter, Najeeb Batool, Sundas Hassan, Syed Shams ul Biomol Ther (Seoul) Review Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge’s derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral, antifungal, antimalarial, antitumor, immunosuppressive, and cardiovascular activity. Although, the mode of action of many compounds by which they interfere with human pathogenesis have not been clear till now, in this review not only the capability of the medicinal substances have been examined in vitro and in vivo against serious pathogenic microbes but, the mode of actions of medicinal compounds were explained with diagrammatic illustrations. This knowledge is one of the basic components to be known especially for transforming medicinal molecules to medicines. Sponges produce a different kind of chemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. The fact that different diseases have the capability to fight at different sites inside the body can increase the chances to produce targeted medicines. The Korean Society of Applied Pharmacology 2016-07 2016-07-01 /pmc/articles/PMC4930278/ /pubmed/27350338 http://dx.doi.org/10.4062/biomolther.2016.067 Text en Copyright ©2016, The Korean Society of Applied Pharmacology http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Anjum, Komal
Abbas, Syed Qamar
Shah, Sayed Asmat Ali
Akhter, Najeeb
Batool, Sundas
Hassan, Syed Shams ul
Marine Sponges as a Drug Treasure
title Marine Sponges as a Drug Treasure
title_full Marine Sponges as a Drug Treasure
title_fullStr Marine Sponges as a Drug Treasure
title_full_unstemmed Marine Sponges as a Drug Treasure
title_short Marine Sponges as a Drug Treasure
title_sort marine sponges as a drug treasure
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930278/
https://www.ncbi.nlm.nih.gov/pubmed/27350338
http://dx.doi.org/10.4062/biomolther.2016.067
work_keys_str_mv AT anjumkomal marinespongesasadrugtreasure
AT abbassyedqamar marinespongesasadrugtreasure
AT shahsayedasmatali marinespongesasadrugtreasure
AT akhternajeeb marinespongesasadrugtreasure
AT batoolsundas marinespongesasadrugtreasure
AT hassansyedshamsul marinespongesasadrugtreasure