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Marine Sponges as a Drug Treasure
Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge’s derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930278/ https://www.ncbi.nlm.nih.gov/pubmed/27350338 http://dx.doi.org/10.4062/biomolther.2016.067 |
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author | Anjum, Komal Abbas, Syed Qamar Shah, Sayed Asmat Ali Akhter, Najeeb Batool, Sundas Hassan, Syed Shams ul |
author_facet | Anjum, Komal Abbas, Syed Qamar Shah, Sayed Asmat Ali Akhter, Najeeb Batool, Sundas Hassan, Syed Shams ul |
author_sort | Anjum, Komal |
collection | PubMed |
description | Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge’s derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral, antifungal, antimalarial, antitumor, immunosuppressive, and cardiovascular activity. Although, the mode of action of many compounds by which they interfere with human pathogenesis have not been clear till now, in this review not only the capability of the medicinal substances have been examined in vitro and in vivo against serious pathogenic microbes but, the mode of actions of medicinal compounds were explained with diagrammatic illustrations. This knowledge is one of the basic components to be known especially for transforming medicinal molecules to medicines. Sponges produce a different kind of chemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. The fact that different diseases have the capability to fight at different sites inside the body can increase the chances to produce targeted medicines. |
format | Online Article Text |
id | pubmed-4930278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Society of Applied Pharmacology |
record_format | MEDLINE/PubMed |
spelling | pubmed-49302782016-07-15 Marine Sponges as a Drug Treasure Anjum, Komal Abbas, Syed Qamar Shah, Sayed Asmat Ali Akhter, Najeeb Batool, Sundas Hassan, Syed Shams ul Biomol Ther (Seoul) Review Marine sponges have been considered as a drug treasure house with respect to great potential regarding their secondary metabolites. Most of the studies have been conducted on sponge’s derived compounds to examine its pharmacological properties. Such compounds proved to have antibacterial, antiviral, antifungal, antimalarial, antitumor, immunosuppressive, and cardiovascular activity. Although, the mode of action of many compounds by which they interfere with human pathogenesis have not been clear till now, in this review not only the capability of the medicinal substances have been examined in vitro and in vivo against serious pathogenic microbes but, the mode of actions of medicinal compounds were explained with diagrammatic illustrations. This knowledge is one of the basic components to be known especially for transforming medicinal molecules to medicines. Sponges produce a different kind of chemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. The fact that different diseases have the capability to fight at different sites inside the body can increase the chances to produce targeted medicines. The Korean Society of Applied Pharmacology 2016-07 2016-07-01 /pmc/articles/PMC4930278/ /pubmed/27350338 http://dx.doi.org/10.4062/biomolther.2016.067 Text en Copyright ©2016, The Korean Society of Applied Pharmacology http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Anjum, Komal Abbas, Syed Qamar Shah, Sayed Asmat Ali Akhter, Najeeb Batool, Sundas Hassan, Syed Shams ul Marine Sponges as a Drug Treasure |
title | Marine Sponges as a Drug Treasure |
title_full | Marine Sponges as a Drug Treasure |
title_fullStr | Marine Sponges as a Drug Treasure |
title_full_unstemmed | Marine Sponges as a Drug Treasure |
title_short | Marine Sponges as a Drug Treasure |
title_sort | marine sponges as a drug treasure |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930278/ https://www.ncbi.nlm.nih.gov/pubmed/27350338 http://dx.doi.org/10.4062/biomolther.2016.067 |
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