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Spatial selective manipulation of microbubbles by tunable surface acoustic waves

A microfluidic device based on a pair of slant-finger interdigital transducers (SFITs) is developed to achieve a selective and flexible manipulation of microbubbles (MBs) by surface acoustic waves (SAWs). The resonance frequency of SAWs generated by the SFITs depends on the location of its parallel...

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Autores principales: Zhou, Wei, Niu, Lili, Cai, Feiyan, Li, Fei, Wang, Chen, Huang, Xiaowei, Wang, Jingjing, Wu, Junru, Meng, Long, Zheng, Hairong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930446/
https://www.ncbi.nlm.nih.gov/pubmed/27462381
http://dx.doi.org/10.1063/1.4954934
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author Zhou, Wei
Niu, Lili
Cai, Feiyan
Li, Fei
Wang, Chen
Huang, Xiaowei
Wang, Jingjing
Wu, Junru
Meng, Long
Zheng, Hairong
author_facet Zhou, Wei
Niu, Lili
Cai, Feiyan
Li, Fei
Wang, Chen
Huang, Xiaowei
Wang, Jingjing
Wu, Junru
Meng, Long
Zheng, Hairong
author_sort Zhou, Wei
collection PubMed
description A microfluidic device based on a pair of slant-finger interdigital transducers (SFITs) is developed to achieve a selective and flexible manipulation of microbubbles (MBs) by surface acoustic waves (SAWs). The resonance frequency of SAWs generated by the SFITs depends on the location of its parallel pathway; the particles at different locations of the SAWs' pathway can be controlled selectively by choosing the frequency of the excitation signal applied on the SFITs. By adjusting the input signal continuously, MBs can be transported along the acoustic aperture precisely. The displacement of MBs has a linear relationship with the frequency shift. The resolution of transportation is 15.19 ± 2.65 μm when the shift of input signal frequency is at a step of 10 kHz. In addition, the MBs can be controlled in a two-dimensional plane by combining variations of the frequency and the relative phase of the excitation signal applied on the SFITs simultaneously. This technology may open up the possibility of selectively and flexibly manipulating MBs using a simple one-dimensional device.
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spelling pubmed-49304462016-07-26 Spatial selective manipulation of microbubbles by tunable surface acoustic waves Zhou, Wei Niu, Lili Cai, Feiyan Li, Fei Wang, Chen Huang, Xiaowei Wang, Jingjing Wu, Junru Meng, Long Zheng, Hairong Biomicrofluidics Regular Articles A microfluidic device based on a pair of slant-finger interdigital transducers (SFITs) is developed to achieve a selective and flexible manipulation of microbubbles (MBs) by surface acoustic waves (SAWs). The resonance frequency of SAWs generated by the SFITs depends on the location of its parallel pathway; the particles at different locations of the SAWs' pathway can be controlled selectively by choosing the frequency of the excitation signal applied on the SFITs. By adjusting the input signal continuously, MBs can be transported along the acoustic aperture precisely. The displacement of MBs has a linear relationship with the frequency shift. The resolution of transportation is 15.19 ± 2.65 μm when the shift of input signal frequency is at a step of 10 kHz. In addition, the MBs can be controlled in a two-dimensional plane by combining variations of the frequency and the relative phase of the excitation signal applied on the SFITs simultaneously. This technology may open up the possibility of selectively and flexibly manipulating MBs using a simple one-dimensional device. AIP Publishing LLC 2016-06-28 /pmc/articles/PMC4930446/ /pubmed/27462381 http://dx.doi.org/10.1063/1.4954934 Text en © 2016 Author(s). 1932-1058/2016/10(3)/034121/9 All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Regular Articles
Zhou, Wei
Niu, Lili
Cai, Feiyan
Li, Fei
Wang, Chen
Huang, Xiaowei
Wang, Jingjing
Wu, Junru
Meng, Long
Zheng, Hairong
Spatial selective manipulation of microbubbles by tunable surface acoustic waves
title Spatial selective manipulation of microbubbles by tunable surface acoustic waves
title_full Spatial selective manipulation of microbubbles by tunable surface acoustic waves
title_fullStr Spatial selective manipulation of microbubbles by tunable surface acoustic waves
title_full_unstemmed Spatial selective manipulation of microbubbles by tunable surface acoustic waves
title_short Spatial selective manipulation of microbubbles by tunable surface acoustic waves
title_sort spatial selective manipulation of microbubbles by tunable surface acoustic waves
topic Regular Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930446/
https://www.ncbi.nlm.nih.gov/pubmed/27462381
http://dx.doi.org/10.1063/1.4954934
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