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Spatial selective manipulation of microbubbles by tunable surface acoustic waves
A microfluidic device based on a pair of slant-finger interdigital transducers (SFITs) is developed to achieve a selective and flexible manipulation of microbubbles (MBs) by surface acoustic waves (SAWs). The resonance frequency of SAWs generated by the SFITs depends on the location of its parallel...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930446/ https://www.ncbi.nlm.nih.gov/pubmed/27462381 http://dx.doi.org/10.1063/1.4954934 |
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author | Zhou, Wei Niu, Lili Cai, Feiyan Li, Fei Wang, Chen Huang, Xiaowei Wang, Jingjing Wu, Junru Meng, Long Zheng, Hairong |
author_facet | Zhou, Wei Niu, Lili Cai, Feiyan Li, Fei Wang, Chen Huang, Xiaowei Wang, Jingjing Wu, Junru Meng, Long Zheng, Hairong |
author_sort | Zhou, Wei |
collection | PubMed |
description | A microfluidic device based on a pair of slant-finger interdigital transducers (SFITs) is developed to achieve a selective and flexible manipulation of microbubbles (MBs) by surface acoustic waves (SAWs). The resonance frequency of SAWs generated by the SFITs depends on the location of its parallel pathway; the particles at different locations of the SAWs' pathway can be controlled selectively by choosing the frequency of the excitation signal applied on the SFITs. By adjusting the input signal continuously, MBs can be transported along the acoustic aperture precisely. The displacement of MBs has a linear relationship with the frequency shift. The resolution of transportation is 15.19 ± 2.65 μm when the shift of input signal frequency is at a step of 10 kHz. In addition, the MBs can be controlled in a two-dimensional plane by combining variations of the frequency and the relative phase of the excitation signal applied on the SFITs simultaneously. This technology may open up the possibility of selectively and flexibly manipulating MBs using a simple one-dimensional device. |
format | Online Article Text |
id | pubmed-4930446 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | AIP Publishing LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-49304462016-07-26 Spatial selective manipulation of microbubbles by tunable surface acoustic waves Zhou, Wei Niu, Lili Cai, Feiyan Li, Fei Wang, Chen Huang, Xiaowei Wang, Jingjing Wu, Junru Meng, Long Zheng, Hairong Biomicrofluidics Regular Articles A microfluidic device based on a pair of slant-finger interdigital transducers (SFITs) is developed to achieve a selective and flexible manipulation of microbubbles (MBs) by surface acoustic waves (SAWs). The resonance frequency of SAWs generated by the SFITs depends on the location of its parallel pathway; the particles at different locations of the SAWs' pathway can be controlled selectively by choosing the frequency of the excitation signal applied on the SFITs. By adjusting the input signal continuously, MBs can be transported along the acoustic aperture precisely. The displacement of MBs has a linear relationship with the frequency shift. The resolution of transportation is 15.19 ± 2.65 μm when the shift of input signal frequency is at a step of 10 kHz. In addition, the MBs can be controlled in a two-dimensional plane by combining variations of the frequency and the relative phase of the excitation signal applied on the SFITs simultaneously. This technology may open up the possibility of selectively and flexibly manipulating MBs using a simple one-dimensional device. AIP Publishing LLC 2016-06-28 /pmc/articles/PMC4930446/ /pubmed/27462381 http://dx.doi.org/10.1063/1.4954934 Text en © 2016 Author(s). 1932-1058/2016/10(3)/034121/9 All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Regular Articles Zhou, Wei Niu, Lili Cai, Feiyan Li, Fei Wang, Chen Huang, Xiaowei Wang, Jingjing Wu, Junru Meng, Long Zheng, Hairong Spatial selective manipulation of microbubbles by tunable surface acoustic waves |
title | Spatial selective manipulation of microbubbles by tunable surface acoustic waves |
title_full | Spatial selective manipulation of microbubbles by tunable surface acoustic waves |
title_fullStr | Spatial selective manipulation of microbubbles by tunable surface acoustic waves |
title_full_unstemmed | Spatial selective manipulation of microbubbles by tunable surface acoustic waves |
title_short | Spatial selective manipulation of microbubbles by tunable surface acoustic waves |
title_sort | spatial selective manipulation of microbubbles by tunable surface acoustic waves |
topic | Regular Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930446/ https://www.ncbi.nlm.nih.gov/pubmed/27462381 http://dx.doi.org/10.1063/1.4954934 |
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