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Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance

AIMS/HYPOTHESIS: Adipose tissue dysfunction is a prime risk factor for the development of metabolic disease. Bone morphogenetic proteins (BMPs) have previously been implicated in adipocyte formation. Here, we investigate the role of BMP signalling in adipose tissue health and systemic glucose homeos...

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Detalles Bibliográficos
Autores principales: Schulz, Tim J., Graja, Antonia, Huang, Tian Lian, Xue, Ruidan, An, Ding, Poehle-Kronawitter, Sophie, Lynes, Matthew D., Tolkachov, Alexander, O’Sullivan, Lindsay E., Hirshman, Michael F., Schupp, Michael, Goodyear, Laurie J., Mishina, Yuji, Tseng, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930470/
https://www.ncbi.nlm.nih.gov/pubmed/27209464
http://dx.doi.org/10.1007/s00125-016-3990-8