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Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance
AIMS/HYPOTHESIS: Adipose tissue dysfunction is a prime risk factor for the development of metabolic disease. Bone morphogenetic proteins (BMPs) have previously been implicated in adipocyte formation. Here, we investigate the role of BMP signalling in adipose tissue health and systemic glucose homeos...
Autores principales: | Schulz, Tim J., Graja, Antonia, Huang, Tian Lian, Xue, Ruidan, An, Ding, Poehle-Kronawitter, Sophie, Lynes, Matthew D., Tolkachov, Alexander, O’Sullivan, Lindsay E., Hirshman, Michael F., Schupp, Michael, Goodyear, Laurie J., Mishina, Yuji, Tseng, Yu-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930470/ https://www.ncbi.nlm.nih.gov/pubmed/27209464 http://dx.doi.org/10.1007/s00125-016-3990-8 |
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