Safety assessment of rice bran oil in a chicken embryo model

OBJECTIVE: Rice Bran Oil (RBO) is extracted from the outer layer of rice. Little information is available regarding its safety. The present study was conducted to assess its safety in chicken embryo model. MATERIALS AND METHODS: RBO was injected on day 4 of incubation of chickens. The tissues and se...

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Autores principales: Araghi, Atefeh, Seifi, Saeed, Sayrafi, Reza, Sadighara, Parisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930543/
https://www.ncbi.nlm.nih.gov/pubmed/27462559
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author Araghi, Atefeh
Seifi, Saeed
Sayrafi, Reza
Sadighara, Parisa
author_facet Araghi, Atefeh
Seifi, Saeed
Sayrafi, Reza
Sadighara, Parisa
author_sort Araghi, Atefeh
collection PubMed
description OBJECTIVE: Rice Bran Oil (RBO) is extracted from the outer layer of rice. Little information is available regarding its safety. The present study was conducted to assess its safety in chicken embryo model. MATERIALS AND METHODS: RBO was injected on day 4 of incubation of chickens. The tissues and serum samples were collected. Oxidative stress parameters in the liver, kidney and brain and biochemical parameters of serum were measured. The deformities were also investigated. RESULTS: The changes in the liver enzymes activity were not statistically significant. There was significant decrease and increase in lipid peroxidation and glutathione level, respectively. It is suggested that RBO is a natural antioxidant source. Low-density lipoprotein cholesterol (LDL) also decreased. No abnormal findings were observed in the chickens. CONCLUSION: No toxic effect was observed following RBO administration in chicken embryos. This study showed that RBO is not a safety concern.
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spelling pubmed-49305432016-07-26 Safety assessment of rice bran oil in a chicken embryo model Araghi, Atefeh Seifi, Saeed Sayrafi, Reza Sadighara, Parisa Avicenna J Phytomed Short Communication OBJECTIVE: Rice Bran Oil (RBO) is extracted from the outer layer of rice. Little information is available regarding its safety. The present study was conducted to assess its safety in chicken embryo model. MATERIALS AND METHODS: RBO was injected on day 4 of incubation of chickens. The tissues and serum samples were collected. Oxidative stress parameters in the liver, kidney and brain and biochemical parameters of serum were measured. The deformities were also investigated. RESULTS: The changes in the liver enzymes activity were not statistically significant. There was significant decrease and increase in lipid peroxidation and glutathione level, respectively. It is suggested that RBO is a natural antioxidant source. Low-density lipoprotein cholesterol (LDL) also decreased. No abnormal findings were observed in the chickens. CONCLUSION: No toxic effect was observed following RBO administration in chicken embryos. This study showed that RBO is not a safety concern. Mashhad University of Medical Sciences 2016 /pmc/articles/PMC4930543/ /pubmed/27462559 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Araghi, Atefeh
Seifi, Saeed
Sayrafi, Reza
Sadighara, Parisa
Safety assessment of rice bran oil in a chicken embryo model
title Safety assessment of rice bran oil in a chicken embryo model
title_full Safety assessment of rice bran oil in a chicken embryo model
title_fullStr Safety assessment of rice bran oil in a chicken embryo model
title_full_unstemmed Safety assessment of rice bran oil in a chicken embryo model
title_short Safety assessment of rice bran oil in a chicken embryo model
title_sort safety assessment of rice bran oil in a chicken embryo model
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930543/
https://www.ncbi.nlm.nih.gov/pubmed/27462559
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