Leveraging 3D chemical similarity, target and phenotypic data in the identification of drug-protein and drug-adverse effect associations

BACKGROUND: Drug-target identification is crucial to discover novel applications for existing drugs and provide more insights about mechanisms of biological actions, such as adverse drug effects (ADEs). Computational methods along with the integration of current big data sources provide a useful fra...

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Detalles Bibliográficos
Autores principales: Vilar, Santiago, Hripcsak, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930585/
https://www.ncbi.nlm.nih.gov/pubmed/27375776
http://dx.doi.org/10.1186/s13321-016-0147-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930585/
https://www.ncbi.nlm.nih.gov/pubmed/27375776
http://dx.doi.org/10.1186/s13321-016-0147-1

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