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Enhanced therapeutic effect of an antiangiogenesis peptide on lung cancer in vivo combined with salmonella VNP20009 carrying a Sox2 shRNA construct

BACKGROUND: HM-3 is a polypeptide inhibiting angiogenesis. Recent reports suggest that the antitumor effect of angiogenesis inhibitors administered alone might be limited. Cancer stem cells can survive the lack of oxygen and nutrients. To achieve better anti-tumor effect, HM-3 was administered in co...

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Detalles Bibliográficos
Autores principales: Zhao, Changhong, He, Junjin, Cheng, Haoran, Zhu, Zhaohao, Xu, Hanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930618/
https://www.ncbi.nlm.nih.gov/pubmed/27371094
http://dx.doi.org/10.1186/s13046-016-0381-4

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